| 幼龄大鼠血浆和下颌后髁突软骨中PGE2水平的近日节律研究 |
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| 引用本文： | 江之泉,王正荣.幼龄大鼠血浆和下颌后髁突软骨中PGE2水平的近日节律研究[J].华西医科大学学报,1997,28(1):23-25. |
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| 作者姓名： | 江之泉 王正荣 |
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| 作者单位： | [1]华西医大基础医学院 [2]基础医学院 |
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| 摘 要： | 为探讨ＰＧＥ２含量检测的准确性，并为时间治疗学在骨科和口腔科中的应用提供依据，采用时间生物学宏观分析和微观分析法对幼龄大鼠血浆和下颌后髁突软骨中六个时序（０：００、４：００、８：００、１２：００、１６：００、２０：００）的ＰＧＥ２含量水平进行了分析。结果显示，血浆和下颌后髁突软骨二者的ＰＧＥ２含量水平均呈现较强近日节律（Ｐ〈０．０５），且峰值一致（分别为－２８２，－２７９）。血浆和下颌后髁突软骨中
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| 关 键 词： | 下颌后髁突软骨 前列腺素E2 生物节律 血浆 |
Circadian rhythm of PGE2 level in plasma and condylar cartilage of young growing rats] |
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| Z Jiang,Z Wang,X Lei,X Yang,Y Chen.Circadian rhythm of PGE2 level in plasma and condylar cartilage of young growing rats][J].Journal of West China University of Medical Sciences,1997,28(1):23-25. |
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| Authors: | Z Jiang Z Wang X Lei X Yang Y Chen |
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| Institution: | Department of Immunology, School of Basic Medical Sciences, Chengdu. |
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| Abstract: | This paper reports the circadian rhythm of PEG2 level in plasma and condylar cartilage of young frowing rats. The samples were measured at 0:00, 4:00, 8:00, 12:00, 16:00, and 20:00 respectively. The count of PGE2 were determined by RIA and analysed with simple Cosinor and coordination. The results revealed: (1) The levels of PGE2 in plasma and condylar cartilage of young growing rats fluctuated in strong circadian rhythm; (2) The rhythm of PGE2 in plasma between 16:00 and 24:00 was significantly different from that between 4:00 and 12:00, so for analysing PGE2 level in plasma, one should proper sampling time or adjust it to circadian rhythm; (3) The circadian rhythm of PGE2 in condylar cartilage could provide important reference for reatments in dentistry and orthopaedics. |
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