耐甲氧西林葡萄球菌药性分析

耐甲氧西林葡萄球菌是引起医院内感染的重要致病菌。为了解该菌的耐药情况，进而为临床预防与治疗提供依据，我们对不葡萄球菌进行了耐甲氧西林及耐其它１４种常用抗生素和产β－内酰胺酶的测定。结果：耐甲氧西林金黄色葡萄球菌检出率为５６％，耐甲氧西林凝固酶阴性葡萄球菌检出率为４７．６％；耐甲氧西林敏感葡萄球菌对１４种常用抗生素的耐药性及多重耐性均高于甲氧西林敏感凝固酶阴性葡萄球菌；产β－内酰胺酶最高的是耐甲氧西

Resistant antibiotic analysis of methicillin-resistant staphylococcus]

Methicillin-resistant staphylococcus aureus is one of the important patholonic bacteria which cause nosocomial infection. In order to investigate the resistant antibiotic circumstances of this organism and hence provide foundations of prevention and treatment, we determined the resistant rates of 88 staphylococcus strains for methicillin and for other 14 kinds of commonly used antibiotics, and we determined the engendering beta-lactamase. The results showed that the isolation rate of methicillin-resistant staphylococcus aureus (MRSA) was 56%; the rate of methicillin-resistant staphylococcus coagulase-negative (MRSCoN) was 47.6%; the resistance rate and the multi-resistant rate of methicillin-resistant staphylococcus (MRS) for the 14 kinds of antibiotics were higher as compared with those of methicillin-sensitive (MSSA). Among all the tested strains, MRSA was the highest to engender beta-lactamase (92.9%); Methicillin-sensitive staphylococcus coagulase-negative (MSSCoN) was the lowest (39.4%). MRS was sensitive to vancomycin and furantoin. These suggest that when treating this bacterium, we should select these two antibiotics first.