Enterocolitis in immunocompromised patients |
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Affiliation: | 1. Department of Medical Microbiology, Faculty of Medicine, Hitit University, Corum, Turkey;2. Department of Surgery, Faculty of Medicine, Hitit University, Corum, Turkey;3. Department of Medical Microbiology, Faculty of Medicine, Ankara University, Ankara, Turkey;1. Division of Comparative Pathology, Department of Pathology & Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL 33101, USA;2. Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California at Davis, Davis, CA 95615, USA;3. Department of Critical Care, The Animal Medical Center, New York, NY 10065, USA;1. Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, The Hashemite University, PO Box 150459, Zarqa 13115, Jordan;2. School of Veterinary and Life Sciences, Murdoch University, Murdoch, WA 6150, Australia;1. Department of Biomedical and Clinical Sciences “Luigi Sacco”, University of Milan, Milan, Italy;2. III Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Milan, Italy;1. University of Brest, LUBEM EA 3882, SFR 148, and Laboratory of Parasitology and Mycology, Brest University Hospital, Brest, France;2. University of Brest, EA 2216, SFR 148, Institute of Oncology and Hematology, Brest University Hospital, Brest, France;3. Laboratory of Parasitology and Mycology, Saint-Louis hospital, AP-HP and Paris-Diderot University, Sorbonne Paris Cité, Paris, France |
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Abstract: | Diarrhea is a very common complaint among immunocompromised patients, and the most common causes of this and other gastrointestinal complaints in this population differ from those commonly seen in immunocompetent patients. Underlying immunodeficiencies may be associated with particular patterns of gastrointestinal tract injury, and particular immunodeficiencies may lead to increased susceptibility to infection by specific organisms depending upon the etiology of the immune compromise. It is important to become familiar with the causes of gastrointestinal disease in the immunocompromised patient population because prompt and proper treatment is of the essence in this patient group. This review focuses on common causes of enterocolitis in the immunocompromised with attention to primary immunodeficiency disorders, the post-transplant setting, chemotherapy-related injury, and a select group of common or emerging infections. |
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Keywords: | Immunocompromised Immunodeficiency Enterocolitis Bacteria Virus Fungus Parasite |
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