| 雷公藤内酯醇生物贴的稳定性研究 |
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| 引用本文： | 钱丽萍,阙慧卿,林绥,彭华毅,李晓慧,郭舜民. 雷公藤内酯醇生物贴的稳定性研究[J]. 药物评价研究, 2012, 0(3): 182-184 |
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| 作者姓名： | 钱丽萍 阙慧卿 林绥 彭华毅 李晓慧 郭舜民 |
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| 作者单位： | 福建省医学科学研究院;福建省卫生技术学院 |
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| 基金项目： | 福建省科技重大专项(2009YZ0001-1-3);福建省医学创新项目(2009-CX-16);福建省省属公益类科研院所基本科研专项(2011R1034-3) |
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| 摘 要： | 目的研究雷公藤内酯醇生物贴中雷公藤内酯醇在不同条件下的稳定性。方法通过影响因素试验、加速试验、长期留样试验,采用高效液相色谱法,测定雷公藤内酯醇,考察雷公藤内酯醇生物贴的稳定性。结果经过光照、升温、加湿、加速等试验,雷公藤内酯醇生物贴中的雷公藤内酯醇的量变化不大。结论雷公藤内酯醇生物贴在市售包装及贮藏条件下,质量稳定。
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| 关 键 词： | 雷公藤内酯醇生物贴 稳定性 高效液相色谱 |
Study on stability of Triplolide Biological Patches |
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| QIAN Li-ping,QUE Hui-qing,LIN Sui,PENG Hua-yi,LI Xiao-hui,GUO Shun-min. Study on stability of Triplolide Biological Patches[J]. Drug Evaluation Research, 2012, 0(3): 182-184 |
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| Authors: | QIAN Li-ping QUE Hui-qing LIN Sui PENG Hua-yi LI Xiao-hui GUO Shun-min |
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| Affiliation: | 1.Fujian Medical Science Research Institute,Fuzhou 350001,China 2.Fujian School of Health Technology,Fuzhou 350001,China |
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| Abstract: | Objective To study the stability of Triplolide Biological Patches(LTBP).Methods Triplolide content was determinated by HPLC method through strengthen test,accelerated test,and long-term restained sample testing.And the stability of LTBP was investigated.Results Triptolide was relatively stable due to light,temperature,humidity,accelerated testing,and long-term testing.Conclusion The results show that LTBP could be relatively stable in the commercial packaging and storage condition in market. |
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| Keywords: | Triplolide Biological Patches(LTBP) stability HPLC |
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