谱效结合在中药提取纯化工艺研究中的应用

如何实现对中药安全性及有效性的合理评价是目前中药质量评价体系面临的主要难题。中药质量的优劣直接影响其临床疗效,缺乏客观、科学的质量评价标准已成为制约中药现代化的一大瓶颈。中药的制备工艺对中药的质量具有很大影响,提取纯化是其中的重要环节。本文简要介绍了谱效结合技术在优化中药提纯工艺中的应用进展,以及在中药制剂质量控制中的作用。

Application of fingerprint-efficacy in studies of extraction and purification method of traditional Chinese medicine

To build a effective method to evaluate the safety and efficacy of TMC was a main problem in TMC quality control system.The TMC quality affected the clinical curative effect directely,which was the bottle neck of the TMC modernization according to the deficiency of an objective and scientific quality control standard.The preparation method would affect the quality of TCM and the key link was extraction and purification.The application of fingerprint-efficacy in optimizing the extraction and purification method of TCM and its effect on quality control of TCM were reviewed in this paper.