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中药注射剂不良反应原因分析及对策
引用本文:郭旭辉,张娜,李林森.中药注射剂不良反应原因分析及对策[J].药物评价研究,2012(3):216-219.
作者姓名:郭旭辉  张娜  李林森
作者单位:中央民族大学中国少数民族传统医学国家民委-教育部重点实验室
基金项目:教育部“长江学者和创新团队发展计划”资助(IRT0871);中央高校基本科研业务费专项资金(1112KYQN43)
摘    要:通过回顾近年来中药注射剂不良反应的相关文献,主要从药物自身因素、生产过程中存在的问题、临床应用中的问题等方面分析中药注射剂临床不良反应事件发生的原因,提出严格规范药品质量的监控,建立统一的质量标准;坚持辨证用药,注意药物的配伍;控制用药剂型及剂量等方面减少中药注射剂不良反应。

关 键 词:中药注射剂  不良反应  对策

Cause analysis on adverse reaction of Chinese materia medica injection and countermeasures
GUO Xu-hui,ZHANG Na,LI Lin-sen.Cause analysis on adverse reaction of Chinese materia medica injection and countermeasures[J].Drug Evaluation Research,2012(3):216-219.
Authors:GUO Xu-hui  ZHANG Na  LI Lin-sen
Institution:State Nationalities Affairs Commission and Department of Educational Key Lab of Minority Traditional Medicine,MINZU University of China,Beijing 100081,China
Abstract:Through the review on the adverse drug reaction(ADR) relevant reports of Chinese materia medica injection(CMMI) in recent years,we found that the major factors led to the ADR are as follows:the herbs or medicines of themselves,the problems appeared during the production process,and the factors appeared in clinical application.Therefore,we put forward the following suggestions:Establishing a unified standard for the medicine quality and strengthen the monitoring of it;Insisting on the utilization of different medicines according to various syndrome,paying attention to the compatibility of the drugs during the clinical application,and choosing the proper dosage of the drug and dosage form.Various links should be standardized in clinical application of CMMI so as to achieve the aim of clinical treatment.
Keywords:Chinese materia medica injection(CMMI)  adverse drug reaction(ADR)  countermeasures
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