口服抗微生物药品服药时间调查分析

目的调查分析口服抗微生物药品的服药时间,为患者合理用药提供参考。方法参考第17版《新编药物学》、《中国医师药师临床用药指南》及药品说明书的相关项目,对体现服药时间的口服抗微生物药按通用名进行分类、统计。结果所调查169种口服抗微生物药品中,要求空腹服用44种,餐时服用30种,餐后服用21种,与进食关系不大的26种,未作具体要求的37种,对进食食品有特殊要求的11种,其中,有1种药品要求空腹或餐后服用,2种要求餐时或餐后服用,4种要求空腹或餐时服用。结论口服抗微生物药品服药时间要求差别很大,需根据具体情况服用,临床药师在临床药学实践及药房药品调配工作中要做好用药交代工作,促进合理用药。

Investigation and analysis of medication time of oral anti-microbial drugs

Objective To investigate and analyze the medication time of oral anti-microbial drugs,in order to provide suggestion for patients on reasonable medication.Methods Medication time of oral anti-microbial drugs were investigated by categories,on the basis of the 17th edition of New Pharmacology,Medication Guide for Chinese Physicians and Pharmacist and the related items in the package inserts of the drugs.Results Among the 169 kinds of investigated oral anti-microbial drugs,44 kinds had to be taken when the stomach was empty,30 kinds taken during meal,21 kinds taken after meal and 26 kinds’ medication time were not related to meals.37 kinds of drugs had no specific requirements for medication time,while 11 kinds had specific requirements on the food taken.Among 169 kinds of oral anti-microbial drugs,1 kind has to be taken with empty stomach or after meal,2 kinds had to be taken during or after meals and 4 kinds had to be taken with empty stomach or during meal.Conclusion Oral anti-microbial drugs have very different requirement on the medication time.Clinical pharmacists should give clear instructions on medication time in clinical pharmacy practice and pharmacy drug dispense to promote rational drug use.