火焰原子吸收分光光度法测定雷奈酸锶干混悬剂中的锶含量

目的：建立测定雷奈酸锶干混悬剂中锶含量的火焰原子吸收分光光度法。方法：使用含有0．1g·L-1铯离子和5．0g·L-1镧离子的0．1％硝酸溶液对样品进行溶解和稀释，采用空气一乙炔火焰原子吸收光谱法在460．7nm波长处进行测定。结果：当锶的质量浓度在6．30～25．20mg·L-1范围内时，其吸光度和质量浓度线性关系良好，相关系数为0．9997；平均加样回收率为101．4％，RSD为1．8％；测得3批雷奈酸锶干混悬剂中锶含量分别为制剂中锶标示含量的98．7％、99．3％和99．8％。结论：该方法便捷、准确、灵敏度高，适用于雷奈酸锶干混悬剂中锶含量的测定。

Determination of Strontium in Strontium Ranelate Suspension by Flame Atomic Absorption Spectrophotometry

Objective:To establish a flame atomic absorption spectrophotometry method for content determination of strontium in strontium ranelate suspension.Methods:The samples were dissolved and diluted in the 0.1 % nitric acid,which contained 0.1 g ·L-1 cesium ion and 5.0 g ·L-1 lanthanum ion.The air-acetylene flame atomic absorption spectrometry was used to determine the strontium at the detection wavelength of 460.7 nm.Results:The absorbance and concentration of strontium showed a good linear relationship at the range of 6.30-25.20 mg ·L-1,with the correlation coefficient of 0.999 7.The recovery rate was 101.4 % and the RSD was 1.8 %.The content of strontium in three batches of strontium ranelate suspension was determined as 98.7 %,99.3 % and 99.8 % relative to labeled amount,respectively.Conclusion:The method is convenient,accurate and sensitive.It can be applied in the determination of strontium in strontium ranelate suspension.