Do some patients with fragile X syndrome have precocious puberty? |
| |
| Authors: | M G Butler J L Najjar |
| |
| Affiliation: | Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232. |
| |
| Abstract: | We report on an 8 1/2-year-old white girl with fra (X) syndrome; she had mental deficiency, hyperactivity, speech disturbances, slightly prominent ears, mild joint laxity and 20% fra (X) expression. Additional findings include idiopathic precocious puberty and a right ovarian cyst. Ovarian cysts have been reported previously in heterozygous females, but to our knowledge idiopathic precocious puberty is a new finding in this syndrome. Whether precocious puberty is a coincidental finding in this patient or a previously unreported manifestation of the fra (X) syndrome is not clear. |
| |
| Keywords: | |
|
|
