冠心病患者冠脉介入术后发生造影剂肾病的危险因素分析

目的探讨冠心病患者介入诊疗后造影剂肾病（CIN）发生的相关危险因素.方法选择120例接受PCI治疗的冠心病患者为研究对象,根据患者术后48h内的血清肌酐水平变化分为CIN组和非CIN组,并对相关危险因素进行分析.结果 120例接受PCI治疗的冠心病患者中有13例发生CIN,CIN发生率为10.83%,Logistic回归分析显示CIN的危险因素为肾功能不全、糖尿病和造影剂剂量及高龄.结论肾功能不全、糖尿病、造影剂剂量及高龄是PCI术后造影剂肾病发生的危险因素.

Risk Factors of Contrast-induced Nephropathy in Patients with Coronary Heart Disease after Percutaneous Coronary Intervention

Objective To investigate risk factors of contrast-induced nephropathy in patients with coronary heart disease after percutaneous coronary intervention.Methods 120 patients with coronary heart disease who underwent PCI were enrolled in this study.The selected patients were divided into CIN group and non-CIN group according to changes in serum creatinine levels within 48 h after percutaneous coronary intervention,and then we analyzed the related risk factors of contrast-induced nephropathy.Results 13 cases of CIN were found in 120 patients with coronary heart disease who underwent PCI,the incidence of CIN was 10.83%.Logistic regression analysis showed that risk factors of CIN included renal insufficiency,diabetes,contrast agent dose and advanced age.Conclusion Renal insufficiency,diabetes,contrast agent dose and advanced age are risk factors of contrast-induced nephropathy in patients with coronary heart disease after percutaneous coronary intervention.