Carcinoma-in-situ of the testis and invasive growth of different types of germ cell tumours. A revised germ cell theory |
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Authors: | Niels E. Skakkebæ k,Jø rgen G. Berthelsen |
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Affiliation: | Laboratory of Reproductive Biology, University Department of Obstetrics and Gynaecology YA, Rigshospitalet, Copenhagen;University Department of Paediatrics G, Rigshospitalet, Copenhagen;University Department of Gynaecology and Obstetrics, Herlev Hospital, Copenhagen |
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Abstract: | The hypothesis is proposed that seminomas and non-seminomas are histogenetically closely related and both types of germ cell tumours may originate from a common precursor cell: namely the germ cell showing the carcinoma-in-situ pattern. However, it is suggested that the spermatocytic seminoma is an exception as it may originate from spermatocytes. |
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Keywords: | testis germ cell carcinoma-in-situ testicular neoplasia |
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