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Carcinoma-in-situ of the testis and invasive growth of different types of germ cell tumours. A revised germ cell theory
Authors:Niels E. Skakkebæ  k,Jø  rgen G. Berthelsen
Affiliation:Laboratory of Reproductive Biology, University Department of Obstetrics and Gynaecology YA, Rigshospitalet, Copenhagen;University Department of Paediatrics G, Rigshospitalet, Copenhagen;University Department of Gynaecology and Obstetrics, Herlev Hospital, Copenhagen
Abstract:The hypothesis is proposed that seminomas and non-seminomas are histogenetically closely related and both types of germ cell tumours may originate from a common precursor cell: namely the germ cell showing the carcinoma-in-situ pattern. However, it is suggested that the spermatocytic seminoma is an exception as it may originate from spermatocytes.
Keywords:testis    germ cell    carcinoma-in-situ    testicular neoplasia
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