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HIV patients treated with low-dose prednisolone exhibit lower immune activation than untreated patients
Authors:Christa?Kasang,Albrecht?Ulmer,Norbert?Donhauser,Barbara?Schmidt,August?Stich,Hartwig?Klinker,Samuel?Kalluvya,Eleni?Koutsilieri,Axel?Rethwilm,Carsten?Scheller  author-information"  >  author-information__contact u-icon-before"  >  mailto:scheller@vim.uni-wuerzburg.de"   title="  scheller@vim.uni-wuerzburg.de"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author
Affiliation:(1) Institute of Virology und Immunobiology, University of Wuerzburg, 97078 Wuerzburg, Germany;(2) HIV-Intensive Care Unit, Schwabstr. 26, 70197 Stuttgart, Germany;(3) Institute of Virology, Clinical and Molecular Virology, National Reference Center for Retroviruses, University of Erlangen-Nuernberg, Erlangen, Germany;(4) Department of Tropical Medicine, Medical Mission Institute, 97067 Wuerzburg, Germany;(5) Medical Clinic and Policlinic II, University of Wuerzburg, Josef-Schneider-Str. 2, 97080 Wuerzburg, Germany;(6) Bugando Medical Center, Mwanza, Tanzania
Abstract:

Background  

HIV-associated general immune activation is a strong predictor for HIV disease progression, suggesting that chronic immune activation may drive HIV pathogenesis. Consequently, immunomodulating agents may decelerate HIV disease progression.
Keywords:
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