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DNA damage drives accelerated bone aging via an NF‐κB–dependent mechanism
Authors:Qian Chen  Kai Liu  Andria R Robinson  Cheryl L Clauson  Harry C Blair  Paul D Robbins  Laura J Niedernhofer  Hongjiao Ouyang
Affiliation:1. Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;2. Department of Oral Biology, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA;3. Department of Human Genetics, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA;4. University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA;5. Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;6. Pittsburgh Veteran's Affairs Medical Center, Pittsburgh, PA, USA;7. Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;8. Department of Restorative Dentistry and Comprehensive Care, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA;9. Center for Craniofacial Regeneration, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA;10. McGowan Institute of Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Abstract:
Keywords:OSTEOPOROSIS  OSTEOBLASTS  OSTEOCLASTS  BONE  NUCLEOTIDE EXCISION REPAIR  PROGERIA  AGING  NF‐κ  B TRANSCRIPTION FACTOR  ERCC1‐XPF ENDONUCLEASE
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