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IL‐2 promotes the function of memory‐like autoregulatory CD8+ T cells but suppresses their development via FoxP3+ Treg cells
Authors:Afshin Shameli  Jun Yamanouchi  Sue Tsai  Yang Yang  Xavier Clemente‐Casares  Anna Moore  Pau Serra  Pere Santamaria
Institution:1. Julia McFarlane Diabetes Research Centre (JMDRC) and Departments of Microbiology, Immunology and Infectious Diseases, Snyder Institute for Chronic Diseases, the University of Calgary, , Calgary, AB, Canada;2. Department of Biochemistry and Molecular Biology, Faculty of Medicine, the University of Calgary, , Calgary, AB, Canada;3. Molecular Imaging Laboratory, MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, , Charlestown, MA, USA;4. Institut d'Investigacions Biomédiques August Pi i Sunyer – Hospital Clinic de Barcelona, , Barcelona, Spain
Abstract:
Keywords:Autoregulatory T‐cell memory  CD122  FoxP3+CD25+ Treg cells  IL‐2  Type 1 diabetes
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