Next‐generation RNA sequencing reveals differential expression of MYCN target genes and suggests the mTOR pathway as a promising therapy target in MYCN‐amplified neuroblastoma期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Next‐generation RNA sequencing reveals differential expression of MYCN target genes and suggests the mTOR pathway as a promising therapy target in MYCN‐amplified neuroblastoma

Authors:	Alexander Schramm Johannes Köster Tobias Marschall Marcel Martin Melanie Schwermer Kathrin Fielitz Gabriele Büchel Matthias Barann Daniela Esser Philip Rosenstiel Sven Rahmann Angelika Eggert Johannes H. Schulte

Affiliation:	1. Department of Pediatric Hematology and Oncology, University Children's Hospital, Essen, GermanyTel.: +49‐201‐7232506, Fax: +49‐201‐7235750;2. Department of Pediatric Hematology and Oncology, University Children's Hospital, Essen, Germany;3. Department of Genome Informatics, University Hospital Essen, Essen, Germany;4. CWI Amsterdam, Statistical Modeling and Comparative Genomics Group, Amsterdam, The Netherlands;5. Department of Computer Science, LS11, University of Dortmund, Dortmund, Germany;6. Institute of Clinical Molecular Biology, Christian Albrechts University, Kiel, Germany

Abstract:

Keywords:	neuroblastoma next‐generation sequencing MYCN mTOR pathway