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Concurrent inhibition of PI3K and mTORC1/mTORC2 overcomes resistance to rapamycin induced apoptosis by down‐regulation of Mcl‐1 in mantle cell lymphoma |
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| Authors: | Anja Müller Chuanbing Zang Cindrilla Chumduri Bernd Dörken Christian W. Scholz |
| Affiliation: | 1. Department of Hematology, Oncology and Tumor Immunology, University Medical Center Charité, Campus Berlin‐Buch, Humboldt University, , Berlin, Germany;2. Clinical and Molecular Oncology, Max Delbrück Center for Molecular Medicine, , 13125 Berlin‐Buch, Germany;3. Department of Oncology and Hematology, University Medical Center Charité, Campus, , Berlin‐Mitte, Germany |
| Abstract: | |
| Keywords: | Mcl‐1 PI3K AKT mTOR signaling mantle cell lymphoma |