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Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo
Authors:Malin Wickström  Takashi Shimokawa  Jelena Milosevic  Ninib Baryawno  Ole M. Fuskevåg  Rolf Larsson  Per Kogner  Peter G. Zaphiropoulos  John I. Johnsen
Affiliation:1. Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, SwedenMalin Wickstr?m and Cecilia Dyberg contributed equally to this work.Tel.: +46‐8‐51772989, Fax: +46‐8‐51773475;2. Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden;3. Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden;4. Department of Clinical Pharmacology, University of Troms?, Troms?, Norway;5. Division of Clinical Pharmacology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden
Abstract:
Keywords:neuroblastoma  Hedgehog signaling  GLI  GANT61
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