阻塞性睡眠呼吸暂停低通气综合征患者血脂水平测定及临床意义 |
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引用本文: | 孟庆华,李承红,江城,孔彬.阻塞性睡眠呼吸暂停低通气综合征患者血脂水平测定及临床意义[J].中国当代医药,2011(31):66-67. |
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作者姓名: | 孟庆华 李承红 江城 孔彬 |
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作者单位: | 湖北省武汉市江汉大学附属医院呼吸科 |
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摘 要: | 目的:探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者血脂水平及临床意义。方法:分析总结2009年12月~2010年12月77例OSAHS成人患者的血脂水平,并与60例正常人血脂水平对照,进行统计学对比及分析。结果:OSAHS组患者吸烟率、体重、BMI高于对照组,差异有统计学意义(P〈0.05)。OSAHS组较对照组TC、TG、TC/HDL明显升高,HDL-C、apo-A降低,两组间比较差异有统计学意义(P〈0.05)。呼吸暂停/低通气指数(AHI)、最长呼吸暂停时间(LAT)、最低血氧饱和度(MinSaO2)行相关分析提示血浆TG水平与AHI呈正相关(r=0.28,P〈0.05),而与MinSaO2呈负相关(r=0.32,P〈0.05)。结论:OSAHS患者常合并代谢功能紊乱,对OSAHS患者及早诊断并给以治疗,可有效改善患者的生活质量和预防相关并发症的发生,提高生活质量。
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关 键 词: | 阻塞性睡眠呼吸暂停低通气综合征 血脂 代谢紊乱 临床意义 |
Research on blood lipid levels in patients with obstructive sleep apnea-hyponea syndrome |
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Authors: | MENG Qinghua LI Chenghong JIANG Cheng KONG Bin |
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Institution: | Department of Respiratory,Affiliated Hospital of Jianghan University,Hubei Province,Wuhan 430015,China |
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Abstract: | Objective:To find out the amount and clinical significance of blood lipid of obstructive sleep apnea hypopnea syndrome(OSAHS) patients.Methods:Analyzed and summarized 77 cases from December 2009 to December 2010,consecutive patients with OSAHS were enrolled(n=77) and the control population consiste of sex-and age-matched healthy subjects(n=60).Results:The smoking rate,body weight,body weight indexof OSAHS patients were higher than the controlled group,the difference was significant(P0.05).TC、TG、TC/HDL of OSAHS patients were higher,but HDL-C,apo-A of OSAHS patients were lower,compared with normal adults.The differences were significant(P0.05).Correlation the analysis showed that plasma TG levels were positively correlated to AHI(r=0.28,P0.05),and negatively correlated to Min SaO2(r=0.32,P0.05).Conclusion:Because of the metabolism mess of OSAHS patients,early diagnosis and treatment could improve patients' life quality and prevent the relative complications. |
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Keywords: | Obstructive sleep apnea hypopnea syndrome(OSAHS) Blood lipid Metabolic disorders Clinical significance |
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