布地奈德及特布他林联合布地奈德治疗小儿哮喘的临床疗效

目的：观察布地奈德及特布他林联合布地奈德治疗小儿哮喘的临床疗效,进而为临床科学合理用药提供依据,提高临床治愈率、减少并发症。方法：选择本院2010年1月～2011年1月收集的100例符合诊断标准而确诊的小儿哮喘急性发作期病例,随机分为对照组和观察组各50例。两组入院后均给予吸氧、抗感染、解痉平喘、镇静等常规治疗,并同时加用布地奈德1～2mg/次,2次/d雾化吸入,观察组在此基础上加用特布他林1.5～2.5mg/次,2次/d雾化吸入,比较两组治疗效果。结果：两组治疗效果比较,观察组治愈率为90%,明显高于对照组的60%,而总有效率观察组和对照组分别为100%及90%,差异均具有统计学意义（P〈0.O5）。结论：应用特布他林联合布地奈德吸入疗法较布地奈德单独吸入具有起效快、治愈率高、并发症少、副作用少的特点,是减少静脉给药的有效方法。

The clinical efficacy of budesonide and terbutaline combined budesonide in treatment of children with asthma

Objective： To observe the clinical efficacy of budesonide and terbutaline combined budesonide in treatment of children with asthma, which in turn to provide the basis for rational and scientific drug use in clinic and to improve the clinical cure rate and reduce complications. Methods： 100 cases of children with asthma in our hospital from January 2010 to January 2011 were met the diagnostic criteria and confirmed the acute exacerbation of asthma in children, they were randomly divided into control group and observation group, there were fifty cases in each group. All of them were given oxygen, antibiotics, antispasmodic asthma, sedative and other conventional treatment, and budesonide 1-2 mg each time, two times a day inhalation, while based on this the observation group were given terbutaline 1.5-2.5 mg each time, two times a day inhalation, then compared the therapeutic effect of the treatment. Results： After the treatment the cure rate of observation group was 90%, which was significantly higher than that of control group which was 60%, while the total effective rate was 100% and 90%, the differences were statistically significant （P0.05）. Conclusion： Compared with budesonide inhalation alone, terbutaline combined with budesonide inhalation with a fast onset, high cure rate, fewer complications, less side effects and characteristics, which is an effective way to reduce the intravenous administration.