4164株病原菌的临床分布及药敏试验结果分析

目的 分析4 164株病原菌的临床分布和药敏试验结果,为控制医院感染和抗菌药物的合理使用提供依据.方法 回顾性分析2010年南京市第一医院4 164株病原菌的临床分布及对抗菌药物的药敏试验结果.结果 4 164株病原菌中(真菌除外),革兰阳性球菌为855株(20.5％),以葡萄球菌属最多(552株),其次为肠球菌属(303株).葡萄球菌属对万古霉素和呋喃妥因高度敏感；屎肠球菌对多数药物的耐药率高于粪肠球菌,粪肠球菌出现耐万古霉素菌株(1.7％).结论 重视病原菌临床分布及耐药性监测,对控制院内感染和病原菌耐药性的发展及临床抗菌素的合理使用有重要指导作用.

Clinical distribution and drug susceptibility testing of 4164 pathogens

Objective To analyze the clinic distribution and drug susceptibility testing of 4164 pathogenic strains, and to provide guidance for the control of hospital infections and the rational use of antibiotics. Methods We retrospectively analyzed the clinic distribution and drug susceptibility testing of 4 164 pathogenic strains in the Nanjing Hospital in 2010. Results A total of 4 164 pathogenic strains were isolated (except fungus), of which 929 strains were gram positive coccus (22.3%), including 596 strains of staphylococcus and 333 strains of enterococcus. Staphylococcus were found to be highly sensitive to nitrofurantoin and Vancomycin, and Enterococcus faecium were found to have a higher sensitivity rate to most drugs than Enterococcus faecalis, which was resistant to vancomycin (1.7%). Conclusion It is important to pay attention to the clinic distribution of pathogenic bacteria and detection of drug resistance, which provides guidance for the control of hospital infections and the rational use of antibiotics.