应用数字化钛网塑形修补颅骨缺损

背景：颅骨修补的材料种类繁多，而修补效果也不尽相同，采用何种修补材料、如何将颅骨缺损修复的更加完美是当前国内外学者研究的热点。 目的：针对数字化三维塑形钛网在颅骨缺损修补中的临床应用进行探索。 方法：以“tissue engineering，craniocerebral trauma，CAD/CAM和titanium armor plate”为检索词，检索Medline数据库(2000/2011-06)，“头颅骨损伤，数字化三维成形，钛网”为检索词，检索CNKI数据库。将近年发表的针对性强的文章纳入研究范围，同一领域的文献则选择近期发表或权威杂志的文章。排除与传统材料或方法修复头颅骨损伤和陈旧的文献。对查阅到的最新研究及临床应用有实用价值的文献详细分析并加以总结概括。 结果与结论：初次检索到236篇文献，最终纳入27篇文献进行分析。传统方法修复颅骨损伤已暴露很多问题，而钛网作为近几年临床应用广泛的颅骨修补材料显示了很多优点，尤其是随着数字化技术的广泛应用，头颅CT扫描数据、三维重建模拟缺损颅骨形状和曲度、个性化设计缺损颅骨的钛网补片，制造出了与缺损处吻合良好的修补物，使患者颅骨缺损修补后头颅形状恢复解剖原貌，无论是整形外观还是相容性方面均可取得满意效果。

Applications of digital shaping titanium armor plate in skull defect repair

BACKGROUND:A wide range of materials with varying repair effects are applicated in skull repair. How to perfecting the skull defect repair and how to choose the right repair materials are the research hotspots for researchers in the world. OBJECTIVE:To explore the clinical application of digital three-dimensional shaping titanium armor plate in skull defect repair. METHODS:An online search of Medline database (2000/2011-06) and CNKI was performed for relevant articles, using keywords of “tissue engineering, craniocerebral trauma, CAD/CAM, titanium armor plate” in English and Chinese, respectively. Articles with high pertinence published in recent years were included in the study. As to the identical field, the articles published recently or in authoritative magazines were selected. Outdated documents and articles repetitive to conventional materials and methods for skull defect repair were excluded. Articles involved the latest research progress and clinical application with practice value were thoroughly analyzed and summarized. RESULTS AND CONCLUSION:A total of 236 articles were collected in the initial search, and 27 of them were retained. Conventional repair methods for skull defect exposed many problems, while titanium armor plate, as skull repair materials widely used in clinic recently, has many advantages. Especially with the wide application of digital technology, repair material which is well match with the defect can be manufactured based on head CT scan, simulation of defect skull shape and curvature by three-dimensional reconstruction, individual design of titanium patch for defect skull. Patients’ head shape reinstate anatomically after skull defect repair. Satisfactory effects are received in appearance and compatibility.