腹腔镜与开腹手术对直肠癌患者术后性功能及膀胱功能影响的系统评价

背景：腹腔镜手术治疗直肠癌在安全性及有效方面均达到或优于传统开腹手术,但可能引起性功能及膀胱功能障碍,而传统开腹术后性功能及膀胱功能障碍发生报道也存在争议。 目的：比较腹腔镜手术与开腹手术对直肠癌患者术后性功能及膀胱功能的影响。 方法：计算机检索PubMed,EMbase,Cochrane library,中国生物医学文献数据库、万方数据库、中国期刊全文数据库、中文科技期刊全文数据库,收集腹腔镜手术对比开腹手术治疗直肠癌患者的随机对照试验。由2名研究者独立按照纳入标准筛选文献、提取资料并交叉核对,采用Cochrane系统评价员手册4.2.6文献质量评价标准评价纳入研究质量,用RevMan 5.0软件进行 Meta分析。 结果与结论：共纳入3个研究,共计347例患者。结果显示与开腹手术比较,腹腔镜术后无论是男性患者或女性患者总在性功能障碍、膀胱功能障碍方面无显著性差异,但尚需要多中心大样本的随机对照试验进一步证实。

Laparoscopic versus open surgery effects on sexual function and bladder function of patients with rectal cancer: A systematic review

BACKGROUND:The laparoscopic surgery exhibit superiority to traditional open surgery in safety and effectiveness in the treatment of rectal cancer, but it may result in sexual and bladder functional disorders. Whether traditional open surgery can lead to sexual and bladder functional disorders remain in dispute.  OBJECTIVE:To compare the effect of laparoscopic and open surgery on sexual function and bladder function in treatment of rectal cancer. METHODS:Literatures related to randomized controlled trials in English and Chinese on the comparison between the sexual function and bladder function after laparoscopic and open surgery in rectal cancer from EMbase, PubMed, CJFD, CBM, Wanfang, CSFD Data were extracted and methodological quality were evaluated by two reviewers independently with designed extraction form. The Cochrane Collaboration’s RevMan 5.0 software was used for data analyses. RESULTS AND CONCLUSION:A total of 3 studies involving 347 patients were included. The results of meta-analyses showed that, there were not significantly different between the laparoscopic and open surgery for rectal cancer in overall sexual function and bladder function, but the results required further investigation.