几种常用载银抗菌材料改性方式的研究现状

背景：银系抗菌剂具有生物安全性高,抗菌谱广,不产生耐药性等特点,是口腔无机抗菌剂中研究的热点。 目的：围绕几种常用银系无机抗菌剂载体结构、载银原理及对其载银方式、载银环境等改性增强其抗菌效果和改善原材料缺陷的研究现状作以综述。 方法：应用计算机检索CNKI数据库、OVID数据库2000/2010有关银系抗菌剂及其载体的相关文章。 结果与结论：无论是传统的沸石、磷酸盐等载体,还是新型的纳米载银方式,人们都从材料本身特征及其载银特质方面不断改性,以期得到用量更少,抑菌性能更优及克服了变色等性能缺陷的优质载银抗菌剂。以后载银无机抗菌材料的开发,除了可以更进一步地利用纳米载银以外,还可以往复合抑菌,缓释抑菌以及将抑菌作为其他材料的添加辅助性能等方面发展。

Research status of modification methods for some silver-carrying antibacterial agents

BACKGROUND:Silver-carrying antibacterial agent has become a research hotspot in inorganic antibacterial agents for oral cavity, because of high biosafety, super antibacterial activity and no drug toletance. OBJECTIVE:To summarize the structure and silver-carrying principle of some common anti-bacterial agent as well as their modification way (silver-carrying approach, silver-carrying environment) on the anti-bacterial effect, improving the defects of raw materials. METHODS:A computer-based online search of CNKI and OVID database from 2000 to 2010 was performed for articles about the silver-carrying anti-bacterial agents and their carriers. RESULTS AND CONCLUSION:No matter traditional zeolite, phosphate and other carriers, or new nano-silver, people are continuously modifying the self characteristics and silver-carrying of the materials so as to obtain a silver-carrying antibacterial agent, through the modification, we hope that the dosage can be reduced and the antibacterial activity can be increased beside their shortage. The expectant silver-carrying antibacterial agent can not only depend on the nanotechnology, but also the combine material, sustained-release and becoming an accessory.