骨水泥灌注在脊柱外科的临床应用

背景：作为微创脊柱外科领域的新技术，经皮椎体穿刺受到了人们的广泛关注，应用骨水泥灌注临床治疗老年性骨质疏松性压缩骨折、稳定性脊柱骨折、脊柱肿瘤及类肿瘤有了很大的发展。目的：对国内外骨水泥灌注在脊柱外科的临床应用现状及新进展作一综述。方法：应用计算机检索CNKI数据库和Pubmed数据库中2005-01/2009-12关于椎体成形方面的文章，在标题中以“经皮椎体成形”或“PVP”为关键词初检得到748篇文献，以关键词“PKP，SKY，压缩性骨折，脊柱肿瘤”为检索词再次在以上数据中进行检索。选择文章内容与脊柱骨水泥灌注有关者，同一领域文献则选择近期发表或发表在权威杂志文章59篇，全文浏览，根据纳入标准选择关于骨水泥灌注方面代表性文献26篇进行综述。另外2篇来自OVID骨科在线英国脊柱。结果与结论：经皮穿刺骨水泥灌注对老年骨质疏松性脊柱压缩骨折、中青年稳定性脊柱骨折、脊柱转移肿瘤或脊柱类肿瘤引起的疼痛，疗效卓越，以其操作简单、手术时间短、医疗费用低、严重不良并发症发生率低等特点被广大患者和专科医务人员接受，随着新型骨水泥的研发，骨水泥灌注在脊柱外科的临床应用必将更加广泛。

Clinical application of bone cement injection in spinal surgery

BACKGROUND:As a new technology in the field of minimally invasive spinal surgery, percutaneous vertebroplasty (PVP) has aroused wide concern. The application of bone cement injection has got great development in senilely clinical osteoporotic vertebral compression fracture (OVCF), stable fracture spinal, spinal tumor, and carcinoid tumor. OBJECTIVE:To summarize the clinical application and advances of bone cement injection in spinal surgery both at home and abroad. METHODS:Within the database CNKI and Pubmed (http://www. ncbi.nlm. nih.gov/sites/entrez) to search the articles about vertebroplasty (2005-01/2009-12), with “vertebroplasty” or “PVP” as key words. Within the 748 articles as results, articles on “PKP”, “SKY”, “compressed fracture” and “spinal tumor” were retrieved, again. Fity-nine articles about spinal bone cement injection were selected, and lately published or on authoritative magazines were chosen if in the same field. Finally, 26 typical  articels about spinal bone cement injection were selected after browsing the whole passage according the standards, together with another two from OVID ONLINE.   RESULTS AND CONCLUSION:Percutaneous bone cement injection shows remarkable effects on senile OVCF, stable spinal fracture in the young and middle aged, spine metastatic tumour, or pain induced by spine carcinoid tumour. With the characteristics as simple operation, short duration of surgery, and fewer serious complications, it is widely accepted by most patients and professional medical staff. As the research and development of new bone cement technology, bone cement injection will be more widely applied in spinal surgery.