人工关节置入材料的临床应用

背景：目前人工关节置入材料的研究已取得了显著的成果，但仍存在一些问题。 目的：综述人工关节置入生物材料的临床应用及研究进展。 方法：应用计算机检索2000-01/2010-10维普数据库有关人工置入材料临床应用方面的相关文献。检索关键词：人工置入材料。 结果与结论：缺损骨骼的再生修复一直是骨研究领域的重要课题。目前常用的治疗方式主要有自体骨移植、异体骨移植和人工骨移植。用人工材料修复骨缺损避免了患者自身取材的痛苦和并发症及同种异体骨免疫排斥的危险，但要求替代材料无毒副作用，有良好的组织兼容性和细胞兼容性。

Clinical application of artificial joint materials

BACKGROUND:Currently, studies about artificial joint materials have achieved remarkable results, but there are still some problems. OBJECTIVE: To review the clinical application and progress of artificial joint biomaterials. METHODS: A computer-based search of VIP database (2000-01/2010-10) was performed to retrieve articles regarding clinical application of artificial joint materials using the keyword of “artificial implant materials”. RESULTS AND CONCLUSION:Regeneration of bone defects has been an important issue in bone research. Currently, the main treatments are autologous bone graft, allograft and artificial bone graft. Repair of bone defects with artificial materials avoids the pain of patients suffering from autologous transplantation, complications and immune rejection due to allogeneic transplantation. But, non-toxic alternative materials are necessary with good cell compatibility and tissue compatibility.