中药促进间充质干细胞的增殖与分化

背景：间充质干细胞是再生医学研究的热点，中药干预间充质干细胞为再生医学的研究注入了新的活力。目的：回顾与总结近年来间充质干细胞研究过程中加入中药干预的研究，旨在进一步探索中医药与间充质干细胞研究的结合点和发展趋势。方法：以“中药”或“中草药”和“间充质干细胞”为检索词，检索CNKI数据库，以 “traditional Chinese medicine”或“herbal medicine”或“Botanical Drugs”和“mesenchymal stem cells” 为检索词检索Pubmed医学数据库。结果与结论：检索到符合纳入标准的文献共35篇。结果显示许多中药及复方对间充质干细胞增殖与分化有促进作用，具有安全、易于在临床推广使用等特点。而且中药在间充质干细胞体内存活等方面具有重大潜力。

Traditional Chinese medicine promotes proliferation and differentiation of mesenchymal stem cells

BACKGROUND:Mesenchymal stem cells are the hotspot in regenerative medicine research, and traditional Chinese medicine (TCM) can improve the efficacy of mesenchymal stem cells therapy.OBJECTIVE:To review the correlation between TCM and stem cells, and to further explore their development trend. METHODS:A computer retrieve of CNKI and PubMed databases using the key words of which were “traditional Chinese medicine” or “herbal medicine” or “Botanical Drugs” and “mesenchymal stem cells” in Chinese and English was performed. RESULTS AND CONCLUSION:Totally 35 articles were included. The results showed that many Chinese herbs and compound play a role in improving the proliferation and differentiation of mesenchymal stem cells, which is safe and easy to clinical application. In addition, Chinese herbs have a great potential to survive in mesenchymal stem cells.