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临床药师对婴幼儿万古霉素血药浓度监测情况分析(英文)
引用本文:张金莲,周佳,陈霁晖,陈婷,刘艳,田怀平,张健. 临床药师对婴幼儿万古霉素血药浓度监测情况分析(英文)[J]. 中国药学, 2015, 24(4): 263-266. DOI: 10.5246/jcps.2015.04.035
作者姓名:张金莲  周佳  陈霁晖  陈婷  刘艳  田怀平  张健
作者单位:上海交通大学附属新华医院药剂科
摘    要:临床药师对2013–2014年婴幼儿病区使用万古霉素的患儿进行血药浓度监测,根据监测结果进行调整用药剂量。此文章对监测结果进行分析总结,讨论万古霉素在新生儿中监测的必要性以及临床药师在此过程中发挥的作用。分析表明,对新生儿常规进行万古霉素血药浓度监测极其必要,而临床药师对使用万古霉素的患儿进行用药监护,参与到临床治疗方案调整当中,可以增加万古霉素使用的有效性及预防不良反应的发生,是一种新型的治疗模式。

关 键 词:临床药师  万古霉素  婴幼儿  治疗药物浓度监测
收稿时间:2015-01-02

Analysis for the vancomycin plasma concentration data in infants by clinical pharmacists
Jinlian Zhang,Jia Zhou,Jihui Chen,Ting Chen,Yan Liu,Huaiping Tian,Jian Zhang. Analysis for the vancomycin plasma concentration data in infants by clinical pharmacists[J]. Journal of Chinese Pharmaceutical Sciences, 2015, 24(4): 263-266. DOI: 10.5246/jcps.2015.04.035
Authors:Jinlian Zhang  Jia Zhou  Jihui Chen  Ting Chen  Yan Liu  Huaiping Tian  Jian Zhang
Abstract:In the present study, clinical pharmacists monitored the blood concentration of vancomycin in children in the Infant Ward from 2013 to 2014, and the drug dose was adjusted according to its plasma concentration. Moreover, we analyzed the plasma concentration of vancomycin in infants in the hospital from 2013 to 2014. Simultaneously, we also discussed the necessity of regular therapeutic drug monitoring of vancomycin in infants, and the important role of clinical pharmacists was further explored. The results showed that it was necessary to routinely monitor the therapeutic drug in infants. Clinical pharmacists performed medication monitoring, which improved the effectiveness of vancomycin and prevented its adverse effects. In addition, it is a new treatment model for the participation of clinical pharmacists in the clinical treatment.
Keywords:Clinical pharmacists  Vancomycin  Infants  Therapeutic drug monitoring  
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