Lack of interaction between cimetidine and carbamazepine |
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| Authors: | J. Sonne,K. Lü hdorf,N. E. Larsen,P. B. Andreasen |
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| Affiliation: | Medical Department F, Glostrup Hospital, Copenhagen, Denmark;Department of Neurology, Gentofte Hospital, and Glostrup Hospital, Copenhagen, Denmark;Clinical Chemistry Department, Glostrup Hospital, Copenhagen, Denmark |
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| Abstract: | In order to investigate a possible interaction between cimetidine and carbamazepine (CBZ) 7 otherwise healthy epileptic patients on a long-term monotherapy with CBZ were given cimetidine (1 g daily) for 7 days. No significant alterations in steady-state plasma concentration of CBZ and the 10,11-epoxide metabolite (CBZ-E) were demonstrated. |
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| Keywords: | Carbamazepine cimetidine interaction |
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