Corpus Callosal Thickness in Alcoholics |
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| Authors: | CLIVE G HARPER JILLIAN J KRIL |
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| Institution: | Department of Pathology, University of Sydney, Sydney, N.S. W. 2006 &;Department of Anatomical Pathology, Royal Prince Alfred Hospital, Missenden Road, Camperdozun, N.S. W. 2050, Australia |
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| Abstract: | The coronal thickness of the corpus callosum in alcoholics and age- and sex-matched controls was measured in a postmortem study. The alcoholics were found to have a significantly (p <0.001) reduced corpus callosal thickness (3.19 mm) when compared to the controls (4.02 mm). This adds weight to the previous pathological finding of reduced white matter volume in alcoholics, which presumably correlates with brain shrinkage seen on CT scans. A significant linear relationship exists between age and the corpus callosal thickness in controls and the white matter volume and corpus callosal thickness in alcoholics. |
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