Endoscopic and radiographic features of gastrointestinal involvement in vasculitis |
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| Authors: | Hokama Akira Kishimoto Kazuto Ihama Yasushi Kobashigawa Chiharu Nakamoto Manabu Hirata Tetsuo Kinjo Nagisa Higa Futoshi Tateyama Masao Kinjo Fukunori Iseki Kunitoshi Kato Seiya Fujita Jiro |
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| Institution: | Akira Hokama, Kazuto Kishimoto, Yasushi Ihama, Tetsuo Hirata, Futoshi Higa, Masao Tateyama, Jiro Fujita, Department of Infectious, Respiratory and Digestive Medicine, Faculty of Medicine, University of the Ryukyus, Okinawa 903-0125, Japan. |
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| Abstract: | Vasculitis is an inflammation of vessel walls, followed by alteration of the blood flow and damage to the dependent organ. Vasculitis can cause local or diffuse pathologic changes in the gastrointestinal (GI) tract. The variety of GI lesions includes ulcer, submucosal edema, hemorrhage, paralytic ileus, mesenteric ischemia, bowel obstruction, and life-threatening perforation.The endoscopic and radiographic features of GI involvement in vasculitisare reviewed with the emphasis on small-vessel vasculitis by presenting our typical cases, including Churg-Strauss syndrome, Henoch-Schönlein purpura, systemic lupus erythematosus, and Behçet’s disease. Important endoscopic features are ischemic enterocolitis and ulcer. Characteristic computed tomographic findings include bowel wall thickening with the target sign and engorgement of mesenteric vessels with comb sign. Knowledge of endoscopic and radiographic GI manifestations can help make an early diagnosis and establish treatment strategy. |
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| Keywords: | Beh et’s disease Churg-Strauss syndrome Computed tomography Endoscopy Gastrointestinal tract Henoch-Sch nlein purpura Histopathology Lupus mesenteric vasculitis Systemic lupus erythematosus Vasculitis |
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