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Multicenter Automatic Defibrillator Implantation Trial–Cardiac Resynchronization Therapy (MADIT‐CRT): Design and Clinical Protocol |
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| Authors: | Arthur J. Moss Mary W. Brown David S. Cannom James P. Daubert Mark Estes Elyse Foster Henry M. Greenberg W. Jackson Hall Steven L. Higgins Helmut Klein Mark Pfeffer David Wilber Wojciech Zareba |
| Abstract: | The planned MADIT‐CRT trial is designed to determine if CRT‐D will reduce the risk of mortality and HF events by approximately 25% in subjects with ischemic (NYHA class I‐II) and non‐ischemic (NYHA class II) cardiomyopathy, left ventricular dysfunction (EF ≤ 0.30), and prolonged intraventricular conduction (QRS duration ≥ 130 ms). |
| Keywords: | MADIT cardiac resynchronization therapy heart failure |