胆总管囊肿患者与巨细胞病毒感染关系的相关性

目的探索人巨细胞病毒感染与胆总管囊肿的相关性。方法使用人巨细胞病毒荧光定量PCR分别对25例胆总管囊肿和20例对照组患者肝脏组织进行检测,同时进行病理染色和人巨细胞病毒晚期蛋白免疫组化检测。结果对照组均为检测到阳性结果,实验组中,人巨细胞病毒阳性14例（阳性率56%）。免疫组化结果显示阳性蛋白多位于肝细胞、血管内皮细胞、炎症浸润细胞当中,胆管上皮细胞呈强阳性反应。结论胆总管囊肿与人巨细胞病毒感染之间存在密切相关性。

Correlation of congenital choledochal cyst and cytornegalovirus infection

Objective To explore the relationship between human cytomegalovirus and choledochal cyst. Methods Fluorescent quantitative PCR（FQ-PCR） was used to detect the liver tissue of human cytomegaloviru in 25 cases of choledochal cyst and 20 cases of control group. Meanwhile, immunohistochemistry was used to detect the human cytomegalovirus late proteins PP65 with the paraffin section. Results Among 25 cases of choledochal cyst, 14 cases（56%） were found to be positive for HCMV, meanwhile, the immunohistochemistry result showed that PP65 was located in the cytoplasm of infected cells such as liver cells, vascular endothelial cells, bile duct epithelial cells and inflammatory infiltrating cells. Conclusion HCMV has a close relationship with choledochal cyst.