In Vitro Studies on Erythrophagocytosis |
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| Authors: | GREENDYKE, ROBERT M. BRIERTY, ROBERT E. SWISHER, SCOTT N. Trabold, Norma Ryser, Richard |
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| Affiliation: | 1 Departments of Pathology and Medicine, The University of Rochester Schoolof Medicine and Dentistry, Rochester, N. Y., and the Pathology Service, Brooke GeneralHospital, Brooke Army Medical Center, Ft. Sam Houston, Texas.
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| Abstract: | 1. Two systems for the quantitative study of erythrophagocytosis in vitroare described.2. The effects of a number of physical factors, cations, anticoagulants, andmetabolic poisons in these systems are reported.3. Existing views on the mechanism of action of factors influencing phagocytosis are briefly reviewed. The importance of the state of energy metabolismof the phagocyte is stressed.4. The importance of physical, chemical, and metabolic aspects of erythrophagocytic systems is emphasized in connection with the use of erythrophagocytosis as a serologic tool in immunohematology. Submitted on January 15, 1963 Accepted on May 16, 1963 |
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