| 丁螺环酮与氯硝西泮治疗广泛性焦虑症的临床对照研究 |
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| 引用本文： | 商振美,吴多琛,陈光金,邢向忠.丁螺环酮与氯硝西泮治疗广泛性焦虑症的临床对照研究[J].山东精神医学,2004,17(2):82-83. |
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| 作者姓名： | 商振美 吴多琛 陈光金 邢向忠 |
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| 作者单位： | 山东省泰安市精神卫生中心
271021(商振美，吴多琛，陈光金)，山东省泰安市精神卫生中心 271021(邢向忠) |
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| 摘 要： | 目的 评价丁螺环酮治疗广泛性焦虑症的临床疗效和副反应。方法 对 2 88例符合CCMD 3诊断标准的广泛性焦虑症患者 ,随机分为两组 ,分别为丁螺环酮组 (14 4例 ) ,氯硝西泮组 (14 4例 )进行治疗 ,疗程 6周。采用焦虑自评量表 (SAS)、Hamilton焦虑量表 (HAMA)和副反应量表 (TESS)评定疗效和副反应。结果 丁螺环酮与氯硝西泮对广泛性焦虑症均有显著疗效。两组间疗效差异无显著性 ,(P >0 .0 5 ) ,丁螺环酮副反应明显少于氯硝西泮 (P <0 .0 1)。结论 丁螺环酮治疗广泛性焦虑症安全有效 ,副反应轻微。
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| 关 键 词： | 丁螺环酮 氯硝西泮 焦虑症 副反应 |
| 文章编号： | 1009-7201(2004)-02-0082-02 |
| 修稿时间： | 2004年1月19日 |
A comparative study of buspirone and clonazepam in the treatment of patients with generalized anxiety disorder |
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| Shang Zhenmei,Wu Duochen,Chen Guangjin,et al..A comparative study of buspirone and clonazepam in the treatment of patients with generalized anxiety disorder[J].Shangdong Archives of Psychiatry,2004,17(2):82-83. |
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| Authors: | Shang Zhenmei Wu Duochen Chen Guangjin |
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| Institution: | Shang Zhenmei,Wu Duochen,Chen Guangjin,et al.Taian Mental Health Center Shandong 271021,China |
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| Abstract: | Objective To explore the clinical efficacy and side effects of buspirone in the treatment of generalized anxiety disorder.Methods A total of 288 patients who met the criteria of CCMD-3 for generalized anxiety disorder were randomly divided into buspirone group and clonazepam group.The period of study was 6 weeks .The efficacy and side effects were rated with HAMA,SAS and TESS.Results Both drugs had marked efficacy in the treatment of generalized anxiety disorder, and there was no significant difference between two groups.Buspirone had significantly fewer side effects than clonazepam.Conclusion Buspiron is safe and effective with slight side effects for generalized anxiety disorder. |
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| Keywords: | Buspirone Clonazepam Generalized anxiety disorder |
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