Blood changes during physiological sleep

Summary The action of moderate stimulation of excitatory process in the central nervous system upon development of experimental tuberculosis was studied.Mice infected with tuberculosis received caffeine during 7 days before and 41 days after infection (0.05 mg subcutaneously).Macro- and microscopic research has shown that the number and size of tubercles, weight of lungs and spleen and weight coefficients of these organs are larger in mice not injected with caffeine. These mice also revealed some necrotic lesions in lungs which were not observed in mice injected.Thus repeated injections of caffeine increases resistance of animals against experimental tuberculosis and leads to atternuation of the specific process.Submitted by Active Member of the Academy of Medical Sciences of the USSR, V. N. Chernigovsky