正常人群非高密度脂蛋白胆固醇和血致动脉硬化指数水平分析

目的 分析甘油三酯（TG）、总胆固醇（TC）均为正常范围内体检人员的非高密度脂蛋白胆固醇（non-HDL-C）和血致动脉硬化指数（AIP）水平情况,为防治血脂异常提供依据。方法 从2001～2006年在我院体体检的45470人中,选择甘油三酯（TG）、总胆固醇（TC均为正常合适范围内的14855人,同时测定高密度脂蛋白胆固醇（HDL-C）,计算出non-HDL-C、LDL-C、AIP;并按性别及不同年龄段进行分组,将各组进行比较分析。结果 男性non-HDL-C、AIP水平明显高于女性,并随年龄增高而逐渐升高;AIP与TG、non-HDL-C、LDL-C成正相关,non-HDL-CTG、TC、LDL-C、AIP成正相关,两者与HDL-C均成负相关。结论 TG、TC均为正常人群中,仍具有发生动脉粥样硬化危险,且男性高于女性,并随着年龄增高而呈升高趋势,老年组更为明显,应引起重视。

Analysis on Levels of Non-high Density Lipoproterin Cholesterol and atherogenic Index of Plasma in Normal Population

Objective To analyze the levels of non-high density lipoprotein cholesterol(non-HDL-C)and atherogenic index of plasma(AIP)in people with normal concentrations of triglyceride(TG)and total cholesterol(TCH)so as to provide basis for the prevention and control of lipid abnormality.Methods 14,855 people with normal concentrations of triglyceride(TG)and total cholesterol(TCH)were selected from total 45470 people who took physical examination in our hospital in 2001,in which the level of high density lipoprotein cholesterol(HDL-C)was detected.And then non-HDL-C,LDL-C,AIP were calculated and compared among the groups divided by gender and age.Result The level of non-HDL-C and AIP were significantly high in men than in women,and increased with age.AIP was positively correlated with TG,non-HDL-C and LDL-C;non-HLD-C was positively correlated with TG,TC,LDL-C and AIP.The both of AIP,non-HDL-C and HDL-C showed negative correlation.Conclusion TG and TC are risk factors of atherosclerosis in normal population.The risk is higher in men than in women,and increases with age.