我院妇产科抗菌药物在规范化管理前后的应用情况比较分析

目的:考察妇产科实施抗菌药物规范化管理的成效。方法:采用系统抽样法,收集我院规范化管理前后产科剖宫产手术患者病历资料各65份与妇科手术患者病历资料各60份,对其进行总结与对比分析。结果:规范化管理后,术前0.5² h用药者比例显著提高,术前>2 h或术后用药者比例显著降低;用药疗程未超过48 h者比例显著提高,整体用药天数显著缩短;甲硝唑的使用频次显著下降,头孢唑林使用频次显著提高;药物联用比例显著降低;以上比较差异均具有统计学意义(P<0.05)。结论:在妇产科开展抗菌药物的规范化管理,对提升本科抗菌药物使用合理水平的效果肯定,值得进一步深入开展。

Comparative Analysis of the Utilization of Antibacterial Drugs in Obstetrics and Gynecology Department of Our Hospital before and after Standardized Management

OBJECTIVE： To investigate the effect of standardized management of antibacterial drugs in obstetrics and gynecolo- gy department. METHODS： 65 medical records of caesarean operation and 60 medical records of gynecologic operation were col- lected before and after standardized management respectively by using systematic sampling method, and then summarized and ana- lyzed comparatively. RESULTS： After standardized management, the proportion of 0.5-2 h preoperative medication increased signif- icantly, while that of 〉2 h preoperative medication and postoperative medication significantly reduced. The proportion of medica- tion duration 〈48 h and the frequency of cefazolin increased significantly, while the number of medication days, the frequency of metronidazole use and the proportion of drug combination significantly decreased; there were statistical significance （P〈0.05）. CONCLUSIONS： The implementation of standardized management of antibacterial drugs in obstetrics and gynecology department promotes rational use of antibacterial drugs definitely, and it is worthy of further spreading in a deep-going way.