蓝色白癜风一例

患者男，26岁，面部白斑10年余，局部变蓝灰7年。皮损变蓝灰前，曾因外用自配药物而发生接触性皮炎。皮肤科情况：左上唇、颞部有蓝灰色色素沉着，唇部皮损内可见白色毛发。皮肤镜：左上唇部可见蓝灰色斑，深浅不一，形状不规则，局部与白斑相间，白斑内见白色毛发残端。颞部组织病理：表皮局部黑素细胞减少，基底层、基底上层可见色素沉着，真皮浅层血管周围有少量慢性炎症细胞及嗜黑素细胞浸润，真皮汗管周围也见嗜黑素细胞浸润。诊断：蓝色白癜风。患者拒绝再治疗，仍在随访中。

A case of blue vitiligo

Wei Xuhua, Zhang Jiang′an, Yu Jianbin, Li Xiaohong, Zhao Bingjie, Lyu Yan, Shi Weihua Department of Dermatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China Corresponding author: Zhang Jiang′an, Email: zja816@163.com 【Abstract】 A 26-year-old male patient presented with facial depigmented patches for 10 years, some of which turned to blue-grey 7 years prior to the presentation. Before the white patches turned blue-gray, the patient developed contact dermatitis due to topical application of self-made drugs. Skin examination showed blue-gray hyperpigmentation on the left upper lip and in the temporal region, with white hairs in the hyperpigmented lesions on the left upper lip. Dermoscopy revealed irregularly shaped, light to dark blue-gray patches on the left upper lip, which were intermingled with white patches in some regions, and white hair stubs were observed in the white patches. Histopathological examination of temporal lesions showed decreased melanocytes in some regions in the epidermis, pigmentation in both basal and suprabasal layers, perivascular infiltration of a small number of chronic inflammatory cells and melanophages in the superficial dermis, and melanophage infiltration around sweat ducts. Finally, the patient was diagnosed with blue vitiligo. He refused to receive any treatments, and follow-up was under way.