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Plasma cortisol,luteinizing hormone (LH), and prolactin secretory responses to cardiopulmonary bypass
Authors:Hiromasa Yokota  Yasunaru Kawashima  Soichi Hashimoto  Hisao Manabe  Toshio Onishi  Toshihiro Aono  Keishi Matsumoto
Affiliation:Departments of Surgery, Obstetrics and Gynecology, and Second Pathology and The Central Laboratory for Clinical Investigation, Osaka University Medical School, Osaka, Japan
Abstract:We measured the plasma levels of cortisol, luteinizing hormone (LH), and prolactin before, during, and after open heart surgery using cardiopulmonary bypass in seven male patients.The levels of cortisol and prolactin were high immediately before the beginning of perfusion. During and after perfusion, increased secretion of cortisol and prolactin was observed.The secretion of LH increased 30 min after the skin incision, but it decreased to the control levels immediately before perfusion. These levels did not change during and after perfusion. The secretory responses of these hormones during perfusion were almost identical to those in the state of physiological circulation.
Keywords:Address correspondence to Hiromasa Yokota   M. D.   First Department of Surgery   Osaka University Medical School   Fukushima-ku   Osaka   Japan
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