| 重症急性胰腺炎大鼠腹腔脏器血流动力学的变化 |
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| 引用本文： | 许雪峰,靳大勇,吴肇汉. 重症急性胰腺炎大鼠腹腔脏器血流动力学的变化[J]. 中国临床医学, 2003, 10(5): 729-730 |
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| 作者姓名： | 许雪峰 靳大勇 吴肇汉 |
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| 作者单位： | 复旦大学附属中山医院普外科,上海,200032 |
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| 摘 要： | 目的 :研究重症急性胰腺炎大鼠腹腔主要器官的血流动力学变化。方法 :将大鼠随机分成 :重症急性胰腺炎组 (SAP)和对照组 ,术后 12h和 2 4h处死。运用多普勒超声测定胰腺局部动脉血流 (胰头、体交界处 )、门静脉血流、脾动脉血流和肠系膜上动脉血流。结果 :SAP时 ,大鼠胰腺局部动脉血流明显下降 ,术后 12h已有明显下降 (vs对照组P <0 .0 1)。随胰腺炎病程进展 ,胰腺局部血流的下降更严重 (2 4hvs12hP <0 .0 5 )。与此同时 ,门静脉、脾动脉和肠系膜上动脉的血流量也下降 (vs对照组P <0 .0 1)。结论 :重症急性胰腺炎时内脏主要器官血流明显下降
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| 关 键 词： | 重症急性胰腺炎 大鼠 腹腔脏器 血流动力学 |
The Changes of Dynamics on the Splanchnic Blood Flow in Rats with SAP |
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| Xu Xuefeng Jin Dayong Wu Zhaohan. The Changes of Dynamics on the Splanchnic Blood Flow in Rats with SAP[J]. Chinese Journal Of Clinical Medicine, 2003, 10(5): 729-730 |
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| Authors: | Xu Xuefeng Jin Dayong Wu Zhaohan |
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| Abstract: | Objective: To investigate the changes of the splanchnic blood flow in SAP rats and underling meaning. Methods: 36 rats were randomized divided into 2 groups:SAP group ( n =24) and the controls( n =12).SAP groups were subdivided into 2 groups. At 12,24 hours after the induction of SAP.12 rats in each group were sacrificed.12 normal rats were used as controls. The regional pancreatic micvascular blood flow was measured by Dopplar ultrasound,the blood flow of portal vein,spleen artery and superior mesenteric artery were also measured. Results: The regional pancreatic micvascular blood flow decreased significantly in SAP group(P<0.01),and continued to decrease after 24h (vs12h P <0.01).The blood flow of portal vein,spleen artery and superior mesenteric artery also decreased in SAP group.Conclusion: The splanchnic blood flow decrease obviously in SAP rats. |
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| Keywords: | SAP Blood flow |
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