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云南省德宏州2016-2017年新报告中国和缅甸籍HIV感染者中HCV的流行病学特征
引用本文:王继宝,陈晓晨,段星,王译葵,杨锦,杨涛,叶润华,杨跃诚,姚仕堂,段松,何纳.云南省德宏州2016-2017年新报告中国和缅甸籍HIV感染者中HCV的流行病学特征[J].中华疾病控制杂志,2019,23(10):1293-1296,1300.
作者姓名:王继宝  陈晓晨  段星  王译葵  杨锦  杨涛  叶润华  杨跃诚  姚仕堂  段松  何纳
作者单位:678400 芒市,德宏傣族景颇族自治州疾病预防控制中心;200032 上海,复旦大学公共卫生学院流行病学教研室公共卫生安全教育部重点实验室
基金项目:国家重点地区艾滋病防治项目;国家科技重大专项2013zx10004-906国家自然科学基金项目81773485
摘    要:  目的  了解德宏州新报告人类免疫缺陷病毒(human immunodeficiency virus,HIV)感染者中丙型肝炎病毒(hepatitis C virus,HCV)阳性率及其流行病学特征。  方法  采用横断面调查方法,对2016-2017年云南省德宏州新报告的2 196例HIV感染者进行HCV抗体检测。  结果  在HIV感染患者中共检测出HCV阳性694例,阳性率为31.6%。其中,中国与缅甸籍新报告HIV感染者中HCV阳性率分别为14.4%(112/780)、41.1%(582/1 416)。不同国籍中HIV/HCV阳性率均以男性、少数民族如傣族和景颇族、小学及以下文化程度和农民较高。多因素Logistic回归分析模型分析结果显示,在中国籍和缅甸籍感染者中,HIV/HCV合并感染与男性、傣族、经注射吸毒感染HIV及农民均有关联。  结论  云南省德宏州新报告的HIV感染者中有较高的HCV阳性率,中国和缅甸籍HIV/HCV合并感染的流行病学特征各有不同,应对不同国籍的感染者需要采取不同的防控措施。

关 键 词:HIV  HCV  合并感染  中国  缅甸  流行特征
收稿时间:2019-01-14

Epidemiological characteristics of co-infection of hepatitis C virus among newly reported HIV infeced patients in Chinese and Burmese from 2016 to 2017 in Dehong Prefecture of Yunnan Province
Institution:1.Dehong Prefecture Center for Disease Control and Prevention, Mangshi 678400, China2.Department of Epidemiology, School of Public Health, and The Key Laboratory for Public Health Safety of Ministry of Education, Fudan University, Shanghai 200032, China
Abstract:  Objective  To understand the prevalence and epidemiological characteristics of hepatitis C virus (HCV) co-infection among newly reported HIV-infected patients from 2016 to 2017 in Dehong Prefecture of Yunnan Province.  Methods  A cross-sectional survey was conducted to detect HCV antibodies in 2 196 newly reported HIV-infected persons in Dehong Prefecture, Yunnan Province, from 2016 to 2017.  Results  A total of 694 cases(31.6%) were detected antibodies against HCV during HIV-infected persents. The prevalence of HCV co-infection among newly reported HIV-infected patients in Chinese and Burmese was 14.4% (112/780) and 41.1% (582/1 416), respectively. Moreover, the prevalence of HCV co-infection was higher in male, ethnic minorities such as Dai and Jingpo minority, primary school and below and farmers in both Chinese and Burmese. Multivariate Logistic regression model showed that HCV infection was associated with male, Dai minority, HIV infection by injecting drug and famers among Chinese and Burmese reported HIV-infected patients.  Conclusions  The prevalence of HCV co-infection was high among newly reported in Dehong Prefecture of Yunnan Province. Meanwhile, the epidemiological characteristics of HIV/HCV co-infections in Chinese and Burmese are different, thus different prevention and control measures are needed for patients of different nationalities.
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