| 结直肠黏液腺癌与非黏液腺癌化疗疗效差异及其机制 |
| |
| 引用本文： | 范 滨,张艳桥.结直肠黏液腺癌与非黏液腺癌化疗疗效差异及其机制[J].现代肿瘤医学,2019,0(15):2768-2771. |
| |
| 作者姓名： | 范 滨 张艳桥 |
| |
| 作者单位： | 哈尔滨医科大学附属肿瘤医院内八科，黑龙江 哈尔滨 150081 |
| |
| 基金项目： | National Natural Science Foundation of China（No.81672428）;国家自然科学基金课题项目（编号:81672428）；北京希思科临床肿瘤学研究基金项目（编号:Y-MX2016-027）；中国抗癌协会-恒瑞医药创新药临床研究基金项目（编号:KY2017-05） |
| |
| 摘 要： | 结直肠癌的病理类型众多，而黏液腺癌是结直肠癌中一种特殊的病理类型。与结直肠非黏液腺癌相比，黏液腺癌的化疗疗效通常不理想，两者疗效差异的机制可能与结直肠黏液腺癌的分子生物学特征及黏液的物理性质有关。本文对结直肠黏液腺癌和非黏液腺癌化疗疗效差异及其机制作一综述，以期对临床上结直肠黏液腺癌的治疗起到积极的指导作用。
|
| 关 键 词： | 黏液腺癌 化疗疗效 化疗敏感性 |
Research on the efficacy of chemotherapy and mechanism of difference of efficacy for colorectal mucinous adenocarcinoma and non-mucinous adenocarcinoma |
| |
| Fan Bin,Zhang Yanqiao.Research on the efficacy of chemotherapy and mechanism of difference of efficacy for colorectal mucinous adenocarcinoma and non-mucinous adenocarcinoma[J].Journal of Modern Oncology,2019,0(15):2768-2771. |
| |
| Authors: | Fan Bin Zhang Yanqiao |
| |
| Institution: | Internal Medicine，Harbin Medical University Affiliated Cancer Hospital，Heilongjiang Harbin 150081，China. |
| |
| Abstract: | There are many pathological types of colorectal cancer，and mucinous adenocarcinoma is a special pathological type of colorectal cancer.Mucinous adenocarcinoma is a special pathological type of colorectal cancer.Mucinous adenocarcinoma is usually less effective in chemotherapy compared with colorectal non-mucinous adenocarcinoma，the mechanism of difference may be related to molecular biological characteristics and physical properties of mucus in colorectal mucinous adenocarcinoma.This article reviews the chemotherapy efficacy and the mechanism of difference of efficacy for colorectal mucinous adenocarcinoma and non-mucinous adenocarcinoma，in order to provide the positive guidance for the clinical treatment of colorectal mucinous adenocarcinoma. |
| |
| Keywords: | mucinous adenocarcinoma efficacy of chemotherapy chemosensitivity |
|
| 点击此处可从《现代肿瘤医学》浏览原始摘要信息 |
| 点击此处可从《现代肿瘤医学》下载免费的PDF全文 |
