外泌体在肺癌中的研究进展

外泌体（exosomes）是由多种细胞分泌的具有脂质双分子层结构的纳米级膜囊小泡，其内含有蛋白质、脂质、核酸等大量生物活性物质。研究表明，外泌体在肺癌的发生发展过程中发挥着重要作用，尤其是在肺癌的早期诊断、侵袭和转移、预后评估以及治疗等方面的作用成为目前研究的热点。因此，关于外泌体的研究将在转化医学的研究模式下，为肺癌临床早期诊断、治疗及预后评估带来新的契机。本文对外泌体在肺癌中的研究进展作一综述。

Research progress of exosomes in lung cancer

Exosomes are Nano-sized membrane vesicle with lipid bilayer structure that are secreted by a variety of cells.It contains a large number of bioactive substances,such as protein,lipid,nucleic acid and so on.Research shows that exosomes play an important role in the process of development of lung cancer,especially in the early diagnosis of lung cancer,invasion and metastasis and prognosis assessment and treatment of lung cancer have become the focus of current research.Therefore,the study on exosomes will bring new opportunities for the early diagnosis and treatment of lung cancer and prognosis assessment in the mode of translational medicine.This article reviews the research progress of exosomes in lung cancer.