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有无黄斑中心凹下沉积物的特发性黄斑前膜治疗效果比较
引用本文:黄志坚,陈晓,洪玲,曾苗.有无黄斑中心凹下沉积物的特发性黄斑前膜治疗效果比较[J].眼科新进展,2019,0(12):1174-1177.
作者姓名:黄志坚  陈晓  洪玲  曾苗
作者单位:430070 湖北省武汉市,中国人民解放军中部战区总医院
摘    要:目的 对比观察特发性黄斑前膜有无黄斑中心凹下沉积物手术前后情况。方法 回顾性非随机临床研究。41例41眼特发性黄斑前膜患者分为2组,组1为有黄斑中心凹下沉积物者8例8眼,组2为没有黄斑中心凹下沉积物者33例33眼。所有患者均接受标准经睫状体平坦部三通道25G玻璃体切割联合内界膜剥除术。对比观察两组术前和术后1个月、3个月、6个月的最佳矫正视力(best corrected visual acuity,BCVA)和黄斑中心凹视网膜厚度(central macular thickness,CMT)情况,同时观察并发症发生情况。结果 术后6个月,组1、组2 BCVA分别为(0.65±0.24)logMAR、(0.54±0.26)logMAR,均较术前明显提高,差异有统计学意义(均为P=0.00);两组间术前、术后6个月BCVA差异均无统计学意义(均为P>0.05)。术后6个月,组1、组2 CMT分别为(288.38±64.64)μm、(299.85±37.19)μm,均较术前显著降低,差异均有统计学意义(均为P=0.00);两组间术前、术后6个月CMT相比差异均无统计学意义(均为P>0.05)。随访期间,所有患眼均未见黄斑前膜复发。结论 25G玻璃体切割联合内界膜剥除治疗特发性黄斑前膜,可稳定提高患者的BCVA,促进黄斑结构的恢复,有无黄斑中心凹下沉积物对术后BCVA、CMT无明显影响。

关 键 词:特发性黄斑前膜  黄斑中心凹视网膜厚度  玻璃体切割  黄斑中心凹下沉积物

Subfoveal deposits in idiopathic macular epiretinal membrane
HUANG Zhi-Jian,CHEN Xiao,HONG Ling,ZENG Miao.Subfoveal deposits in idiopathic macular epiretinal membrane[J].Recent Advances in Ophthalmology,2019,0(12):1174-1177.
Authors:HUANG Zhi-Jian  CHEN Xiao  HONG Ling  ZENG Miao
Institution:Department of Ophthalmology,Central War Zone General Hospital,Wuhan 430070,Hubei Province,China
Abstract:Objective To compare the preoperative and postoperative course of subfoveal deposits in idiopathic macular epiretinal membrane(IEM).Methods This retrospective,non-randomised,comparative clinical study.We divided 41 patients (41 eyes) with IEM into 8 eyes of 8 patients with subfoveal deposits as group 1 and 33 eyes of 33 patients without subfoveal deposits as group 2.All patients were treated by 25G micro-incision vitrectomy and internal limiting membrane (ILM) removal.The changes of the best corrected visual acuity(BCVA),central macular thickness(CMT) were compared at preoperative and postoperative 1,3,6 months.Results At the 6 months after surgery,the mean BCVA was (0.65±0.24)logMAR in group 1,and (0.54±0.26)logMAR in group 2,significant postoperative improvements were observed in both groups(both P=0.00);the difference was not significant in both groups at preoperative and postoperative 6 months(both P>0.05).The mean CMT was (288.38±64.64)μm in group 1,and (299.85±37.19)μm in group 2,significant postoperative improvements were observed in both groups(both P=0.00);the difference was not significant in both groups at preoperative and postoperative 6 months(both P>0.05).No patients of IEM was recurrenced during in 6 months.Conclusion 25G micro-incision vitrectomy and ILM removal is an efficient and safe treatment for IEM,they can improve BCVA and foveal morphology.Subfoveal deposits does not significantly influence on postoperative BCVA and CMT.
Keywords:idiopathic macular epiretinal membrane  central macular thickness  vitrectomy  subfoveal deposits
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