宫颈癌临床病理特征与盆腔淋巴结转移的相关性分析

目的 分析宫颈癌临床病理特征与盆腔淋巴结转移之间的关系。 方法 回顾性分析温州市中西医结合医院2015年3月-2017年3月收治的宫颈癌患者102例,其中有盆腔淋巴结转移者共22例(21.57%),作为观察组,其余80例无盆腔淋巴结转移者为对照组,观察并探讨2组患者肿瘤分期、组织学类型、生长类型等与盆腔淋巴结转移之间的关系。 结果 观察组患者中有绝经期9例,占40.91%(9/22),对照组22例,占27.50%(22/80),2组差异有统计学意义(P<0.05)。观察组高危型HPV阳性22例,占100%;Ⅰb 14例,占63.64% (14/22),Ⅱa 8例,占36.36%(8/22);14例肿瘤直径 ≥ 4 cm,占63.64%(14/22)。观察组10例宫颈肌层癌浸润深度>2/3(45.45%),对照组17例(21.25%),2组差异有统计学意义(P<0.05);观察组内生型17例,外生型5例,没有溃疡型及颈管型,与对照组比较差异有统计学意义(P<0.05)。盆腔淋巴结转移与年龄、组织学分型等无明显相关。 结论 宫颈癌患者有高危型HPV、临床分期、肿瘤大小与盆腔淋巴结转移有关,且宫颈肌层癌浸润深度>2/3、内生型的宫颈癌患者,其盆腔淋巴结转移率较高。 

Correlation between clinicopathological features and pelvic lymph node metastasis in cervical cancer

Objective To analyze the relationship between the clinicopathological features of the cervical cancer patients and pelvic lymph node metastasis. Methods We chose 102 cervical cancer patients who were admitted to our hospital from March 2015 to March 2017, including 22 cases with pelvic lymph node metastasis, the metastasis rate was 21.57%, as the observation group, the other 80 cases without pelvic lymph node metastasis as the control group, observed and discussed the two groups of tumor staging, histology type, growth type, and so on. We compared the relationship between the tumor staging, histology type, growth type with pelvic lymph node metastasis. Results In the observation group, there were 9 cases of menopause, 9/22 (40.91%) and 22 cases in the control group, accounting for 22/80 (27.5%), the difference was statistically significant (P<0.05); high risk HPV positive 22 cases, 100%, negative 0 cases; IB 14 cases, 14/22 (63.64%), IIa have 8 cases, accounting for 8/22 (36.36%); there were 14 cases of tumor more than 4 cm, accounting for 14/22 (63.64%), 8 cases of tumor<4 cm, accounting for 8/22 (36.36%), the difference was statistically significant (P<0.05); 10 cases (45.45%) of the invasive depth of cervical myometrium in the observation group, 17 (21.25%) in the control group (21.25%), and statistically significant (P<0.05) in the observation group (P<0.05). There were 17 cases of edophytic type, 5 cases of exophytic type, 0 cases of ulcerative type and cervical type in the observation group, compared with the control group, the difference was statistically significant (P<0.05). Conclusion The patients with cervical cancer have high risk of HPV, the clinical staging and the tumor size are related to the pelvic lymph node metastasis. The adenocarcinoma and endogenetic cervical cancer patients have higher pelvic lymph node metastasis, which provides a reference for the individualized treatment of cervical cancer patients.