原发性膀胱嗜铬细胞瘤一例并文献复习

目的:探讨膀胱嗜铬细胞瘤临床诊疗过程中的特征，以期提高对该病的认识。方法:回顾性分析我院一例膀胱嗜铬细胞瘤患者的临床资料，并检索中国知网、万方、Pubmed等数据库，对相关文献进行系统性分析，归纳其临床特点。结果:本例患者行膀胱部分性切除术，术后一般情况良好，无阵发性血压升高，无头痛尿痛，随访五个月未见进展。结论:膀胱嗜铬细胞瘤是一种罕见的泌尿系肿瘤，有些甚至无特异临床表现。膀胱嗜铬细胞瘤的诊断应该结合临床表现，儿茶酚胺及其代谢产物的检测，再同时结合影像学资料，确诊依靠病理。治疗应以手术切除为主，对于难以切除的膀胱嗜铬细胞瘤可行辅助化疗、放疗等治疗等。【关键词】膀胱嗜铬细胞瘤；膀胱部分性切除术；阵发性高血压；无痛性肉眼血尿

Primary bladder pheochromocytoma:Case report and brief review of the literature

Objective:To discuss the clinical features of pheochromocytoma of bladder，so as to guide the clinical diagnosis and treatment of bladder pheochromocytama.Methods:To analyze retrospectively the clinical data of one case that the patient with bladder pheochromocytama，and retrieval CNKI，Wan Fang，Pubmed and other databases.Systematically analysis of the relevant literature and induce its clinical characteristics was performed.Results:Partial cystectomy was performed in this patient who had good general condition，no paroxysmal blood pressure increased，no headache and urine pain，and no progress was found after 5 months of follow-up.Conclusion:Bladder pheochromocytama is a rare urological tumor.Some don' t even have specific clinical manifestations.The diagnosis of bladder pheochromocytama should be combined with clinical manifestations，the level of catecholamine and its metabolites，combined with imaging data，and the diagnosis depends on the pathological.Treatment should be based on surgical resection.For the unresectable bladder pheochromocytoma，such as adjuvant chemotherapy，radiotherapy and so on are available.