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药物毒性角膜病变的研究进展
引用本文:魏爽,盛敏杰,姜亚萍,陈轶卉. 药物毒性角膜病变的研究进展[J]. 眼科新进展, 2019, 0(10): 988-991. DOI: 10.13389/j.cnki.rao.2019.0226
作者姓名:魏爽  盛敏杰  姜亚萍  陈轶卉
作者单位:200090 上海市,同济大学附属杨浦医院
基金项目:上海市自然科学基金(编号:17ZR1427100);上海市杨浦区重点学科(编号:YP16ZA02);上海市杨浦区中心医院“攀登计划”(编号:Ye2201501);上海市杨浦区好医生建设工程项目~~
摘    要:药物毒性角膜病变通常是指眼局部或全身应用药物所导致的角膜组织病理性改变。药物毒性角膜病变的产生是由于药物本身毒性或药物制剂中所含防腐剂的毒性所致。近年来,随着滴眼剂种类的增多、眼局部药物的滥用和滴药过度导致的药物毒性角膜病变在临床上不断增加。本文就近年关于药物毒性角膜病变的研究进展进行综述,以期为临床角膜疾病的诊断和治疗提供帮助。

关 键 词:角膜病变  药物毒性  眼表

Research progress of drug toxic keratopathy
WEI Shuang,SHENG Min-Jie,JIANG Ya-Ping,CHEN Yi-Hui. Research progress of drug toxic keratopathy[J]. Recent Advances in Ophthalmology, 2019, 0(10): 988-991. DOI: 10.13389/j.cnki.rao.2019.0226
Authors:WEI Shuang  SHENG Min-Jie  JIANG Ya-Ping  CHEN Yi-Hui
Affiliation:Department of Ophthalmology,Yangpu Hospital,Tongji University School of Medicine,Shanghai 200090,China
Abstract:Drug toxic keratopathy means corneal tissue pathological changes due to topical or systemic medications.Drug toxic keratopathy is usually caused by the toxicity of drugs themselves or preservatives contained in pharmaceutical preparations.Recently,drug toxic keratopathy has increased in clinical practice as a result of the variety of eye drops,the abuse of local drugs in the eyes and the excessive frequency of of eye drops.We will give a review on the research progress of drug toxic keratopathy for providing assist for the diagnosis and treatment of clinical corneal diseases.
Keywords:keratopathy   drug toxicity   ocular surface
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