玉女煎联合西药治疗2型糖尿病阴虚热盛证的临床效果

目的 观察玉女煎联合西药治疗2型糖尿病阴虚热盛证的临床效果，以探讨临床治疗该病的有效疗法，促进患者生活质量的提升。 方法 选取仙居县中医院2018年2月—2019年2月收治的96例2型糖尿病患者，随机纳入对照组(n=48)及观察组(n=48)，2组患者分别在常规治疗的基础上给予二甲双胍治疗及玉女煎联合二甲双胍治疗，对比其证候积分变化、临床疗效、血糖水平(空腹血糖、餐后2 h血糖、糖化血红蛋白)以及不良反应发生情况(腹泻、头晕、头痛、皮疹)。 结果 观察组治疗后的证候积分为(5.72±1.81)分，低于对照组的(8.62±2.65)分，观察组总有效率(93.75%)高于对照组(79.17%)，观察组治疗后的空腹血糖、餐后2 h血糖、糖化血红蛋白[(7.31±1.24)mmol/L、(8.72±2.19)mmol/L、(3.82±1.44)%]低于对照组[(8.64±3.37) mmol/L、(13.07±2.35) mmol/L、(5.05±2.18)%)]，差异均有统计学意义(均P<0.05)；观察组不良反应发生率(4.17%)与对照组(6.25%)相近，差异无统计学意义(P>0.05)。 结论 玉女煎联合西药治疗2型糖尿病阴虚热盛证的临床效果显著，可明显降低证候积分，改善患者的血糖水平，不良反应少，值得推行。 

Clinical effect of Yunyu Decotion combined with western medicine in treating type 2 diabetes mellitus with Yin deficiency and heat excess syndrome

Objective To observe the clinical effect of Yunyu Decotion combined with western medicine in treating type 2 diabetes mellitus with Yin deficiency and heat excess syndrome, so as to explore the effective treatment of the disease and promote the improvement of patients' quality of life. Methods A total of 96 patients with type 2 diabetes admitted to our hospital from February 2018 to February 2019 were randomly divided into control group (n=48) and observation group (n=48). The two groups were treated with metformin and Yunyu Decotion combined with metformin on the basis of routine treatment respectively. The changes of syndrome integral, clinical efficacy, blood sugar level (fasting blood sugar, 2 h postprandial blood sugar and glycosylated blood sugar) and adverse reactions (diarrhea, dizziness, headache and rash) were compared between the two groups. Results After treatment, the syndrome score of the observation group (5.72±1.81) was lower than that of the control group (8.62±2.65), the total effective rate of the observation group (93.75%) was higher than that of the control group (79.17%). After treatment, the fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin (7.31 mmol/L±1.24 mmol/L, 8.72 mmol/L±2.19 mmol/L, 3.82%±1.44%) of the observation group were lower than that of the control group (8.64 mmol/L±3.37 mmol/L, 13.07 mmol/L±2.35 mmol/L, 5.05%±2.18%). The incidence of adverse reactions in the observation group (4.17%) was similar to that in the control group (6.25%). There was no significant difference between the two groups (all P>0.05). Conclusion Yunyu Decotion combined with western medicine has a significant clinical effect in treating type 2 diabetes mellitus with Yin deficiency and heat excess syndrome. It can significantly reduce the syndrome score, improve the blood sugar level of patients, and have fewer adverse reactions. It is worth promoting.