2011-2017年苏州市区5岁以下儿童流感相关门诊就诊率的估计

目的  估计2011-2017年苏州市区5岁以下儿童流感相关流感样病例（influenza-like illness，ILI）就诊率。 方法  2011年10月~2017年3月，在苏州大学附属儿童医院门急诊室开展对5岁以下儿童ILI病例的监测。收集咽拭子标本并采用实时定量逆转录-聚合酶链反应进行流感病毒检测。同时基于卫生服务利用数据及人口学数据，估计苏州市区5岁以下儿童流感相关ILI就诊数和就诊率。 结果  2011-2017年苏州市区约有45 930例次5岁以下流感相关ILI病例，其中因流感病毒A/H1N1感染就诊的ILI病例7 490例，A/H3N2就诊数为17 843例，B就诊数为20 597例。研究期间，苏州市区5岁以下儿童流感相关ILI病例的就诊率为6.4/100人年，其中2011-2012年流感相关ILI就诊率最高，达20.5/100人年，2012-2013年最低，为2.4/100人年。 结论  苏州市区5岁以下的儿童流感相关ILI就诊数和就诊率较高，疾病负担较大。

The estimation of influenza-related outpatient rate in children under 5 years in Suzhou from 2011 to 2017

  Objective  To estimate the outpatient rate of influenza-related influenza-like illness (ILI) for children younger than 5 years in Suzhou municipal districts.  Methods  From October 2011 to March 2017, we conducted a prospective surveillance program on ILI for children under 5 years in outpatient settings of Soochow University Affiliated Children's Hospital (SCH). The throat swabs were collected and tested for influenza viruses by RT-PCR. Based on the healthcare utilization surveys and population data, the number of visits and the outpatient rate of influenza-related ILI for children younger than 5 years in Suzhou municipal districts were estimated.  Results  During 2011-2017, in total, there were 45 930 estimated influenza-related ILI cases younger than 5 years in Suzhou municipal districts, which consisted of 7 490 influenza A/H1N1 cases, 17 843 influenza A/H3N2 cases and 20 597 influenza B cases. The estimated outpatient rate of influenza-related ILI was 6.4% in 2011-2017, which was highest in 2011-2012, 20.5%, and the lowest in 2012-2013, 2.4%.  Conclusion  The number of visits and the outpatient rate of influenza-related ILI in children younger than 5 years was high in Suzhou municipal districts.