老年颅内肿瘤术中并发非手术区域血肿的危险因素分析

目的:分析老年颅内肿瘤术中并发非手术区域血肿的危险因素。方法:选择2010年3月至2017年3月在我院行开颅切除手术且并发非手术区域血肿的老年颅内肿瘤患者31例作为血肿组,随机抽取同期在我院行开颅切除手术无血肿的老年颅内肿瘤患者107例作为对照组。对两组老年患者临床资料进行回顾性分析,采用单因素及多因素Logistic回归分析可能造成非手术区域血肿的危险因素。结果:单因素及多因素Logistic回归分析显示,术前合并脑积水、血浆凝血酶时间、术前合并脑萎缩、患者年龄以及肿瘤大小进入回归模型(P<0.05)。对照组患者GOS评分显著优于血肿组(P<0.05)。结论:老年颅内肿瘤术中并发非手术区域血肿对患者术后预后造成不良影响,术前合并脑积水、血浆凝血酶时间、术前合并脑萎缩、高龄以及肿瘤大小是影响患者血肿发生的独立危险因素,针对上述危险因素应采取积极的预防救治措施,以提高治疗效果。

Analysis of risk factors for non-operative hematoma in elderly patients with intracranial tumor

Objective:To investigate and analyze the risk factors of non-operative hematoma in elderly patients with intracranial tumor.Methods:To collect from March 2010 to March 2017 in our hospital underwent craniotomy and resection of intracranial tumors complicated with non-operative regional hematoma in elderly patients 31 cases as hematoma group,and in our hospital underwent craniotomy intracranial tumor resection without hematoma in elderly clinical data of 107 cases as the control group.The clinical data of two groups of elderly patients were retrospectively analyzed.Univariate and multivariate Logistic regression analysis were used to analyze the risk factors of non-operative hematoma.Results:Univariate and multivariate Logistic regression analysis showed that preoperative hydrocephalus,plasma thrombin time,preoperative cerebral atrophy,age and tumor size entered the regression model (P＜0.05).The GOS score of the patients in the control group was significantly better than that in the hematoma group (P＜0.05).Conclusion:Intracranial tumor resection in the elderly with non-operative regional hematoma on the prognosis of patients has adverse effects.Preoperative hydrocephalus,thrombin time,preoperative cerebral atrophy,advanced age and tumor size were independent risk factors of the occurrence of hematoma.According to these risk factors,we should take active preventive measures in order to improve the therapeutic effect.